See our new animation describing muscle regeneration:
A little about our research:
Adult tissue specific stem cells play a critical role in replacing lost tissue, they do not act in isolation and multiple other cell types modulate their function. This ensures that the rebuilding of functional, stromal, vascular and other tissue components is coordinated and follows a temporal and spatial organization compatible with function. Our goal is to identify and characterize these “accessory” cells types as a starting point to understand how they regulate tissue specific stem cells as well as each other, and how such regulation goes awry in pathological situations. In particular, we have focused our attention on the role of innate immune cells and stromal progenitors. In this context our lab works on three research directions, Cellular systems in muscle regeneration, Microglia/macrophages in CNS pathology and Epigenetic control of lineage choice/differentiation.