Name: Farshad Babaeijandaghi
Birthplace: Tehran, Iran
Nationality: Iranian - Canadian
Previous or Current Education: Doctor of Medicine: 2001-2009
Graduate student: 2013-2021
Research Summary: Dissecting the role of innate immunity in muscle regeneration and fibrosis.
Personal Summary: I got my doctoral degree in Medicine from Tehran University of Medical Sciences, Tehran, Iran, in 2009. Then, I started my research career at Stem Cell Technology Research Center, Tehran, Iran as a postdoctoral fellow. I joined the Rossi lab in January 2013 as a graduate student. I defended my thesis in Aug 2021 and I am currently working as a postdoctoral fellow. Outside work, I enjoy biking, hiking, and socializing with friends.
Selected Publications:
1. Babaeijandaghi F, Cheng R, Kajabadi N, Soliman H, Chang CK, Smandych J, Tung LW, Long R, Ghassemi A, Rossi FMV. Metabolic reprogramming of skeletal muscle by resident macrophages points to CSF1R inhibitors as muscular dystrophy therapeutics. Sci Transl Med. 2022 Jun 29;14(651):eabg7504. doi: 10.1126/scitranslmed.abg7504. Epub 2022 Jun 29. PubMed PMID: 35767650.
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2. Smaila BD, Holland SD, Babaeijandaghi F, Henderson HG, Rossi FMV, Ramer MS. Systemic hypoxia mimicry enhances axonal regeneration and functional recovery following peripheral nerve injury. Exp Neurol. 2020 Dec;334:113436. doi: 10.1016/j.expneurol.2020.113436. Epub 2020 Aug 16. PubMed PMID: 32814068.
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3. Pisconti A, Banks GB, Babaeijandaghi F, Betta ND, Rossi FM, Chamberlain JS, Olwin BB. Loss of niche-satellite cell interactions in syndecan-3 null mice alters muscle progenitor cell homeostasis improving muscle regeneration. Skelet Muscle. 2016;6:34. doi: 10.1186/s13395-016-0104-8. eCollection 2016. PubMed PMID: 27757223; PubMed Central PMCID: PMC5064903.
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4. Lemos DR, Babaeijandaghi F, Low M, Chang CK, Lee ST, Fiore D, Zhang RH, Natarajan A, Nedospasov SA, Rossi FM. Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors. Nat Med. 2015 Jul;21(7):786-94. doi: 10.1038/nm.3869. Epub 2015 Jun 8. PubMed PMID: 26053624.
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5. Mortazavi H, Babaeijandaghi F, Akbarzadeh M, Rezaei N, Amirzargar AA, Daneshpazhooh M, Jalali A, Hallaji Z. The influence of systemic therapy on the serum levels of IL-6 and IL-8 in pemphigus vulgaris. J Eur Acad Dermatol Venereol. 2013 Mar;27(3):387-90. doi: 10.1111/j.1468-3083.2011.04319.x. Epub 2011 Nov 2. PubMed PMID: 22044642.
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6. Ahmadbeigi N, Soleimani M, Babaeijandaghi F, Mortazavi Y, Gheisari Y, Vasei M, Azadmanesh K, Rostami S, Shafiee A, Nardi NB. The aggregate nature of human mesenchymal stromal cells in native bone marrow. Cytotherapy. 2012 Sep;14(8):917-24. doi: 10.3109/14653249.2012.689426. Epub 2012 Jun 11. PubMed PMID: 22687188.
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7. Shabani I, Haddadi-Asl V, Soleimani M, Seyedjafari E, Babaeijandaghi F, Ahmadbeigi N. Enhanced infiltration and biomineralization of stem cells on collagen-grafted three-dimensional nanofibers. Tissue Eng Part A. 2011 May;17(9-10):1209-18. doi: 10.1089/ten.TEA.2010.0356. Epub 2011 Jan 26. PubMed PMID: 21143044.
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8. Babaeijandaghi F, Shabani I, Seyedjafari E, Naraghi ZS, Vasei M, Haddadi-Asl V, Hesari KK, Soleimani M. Accelerated epidermal regeneration and improved dermal reconstruction achieved by polyethersulfone nanofibers. Tissue Eng Part A. 2010 Nov;16(11):3527-36. doi: 10.1089/ten.TEA.2009.0829. Epub 2010 Aug 30. PubMed PMID: 20624004.
Contact: [email protected]
Birthplace: Tehran, Iran
Nationality: Iranian - Canadian
Previous or Current Education: Doctor of Medicine: 2001-2009
Graduate student: 2013-2021
Research Summary: Dissecting the role of innate immunity in muscle regeneration and fibrosis.
Personal Summary: I got my doctoral degree in Medicine from Tehran University of Medical Sciences, Tehran, Iran, in 2009. Then, I started my research career at Stem Cell Technology Research Center, Tehran, Iran as a postdoctoral fellow. I joined the Rossi lab in January 2013 as a graduate student. I defended my thesis in Aug 2021 and I am currently working as a postdoctoral fellow. Outside work, I enjoy biking, hiking, and socializing with friends.
Selected Publications:
1. Babaeijandaghi F, Cheng R, Kajabadi N, Soliman H, Chang CK, Smandych J, Tung LW, Long R, Ghassemi A, Rossi FMV. Metabolic reprogramming of skeletal muscle by resident macrophages points to CSF1R inhibitors as muscular dystrophy therapeutics. Sci Transl Med. 2022 Jun 29;14(651):eabg7504. doi: 10.1126/scitranslmed.abg7504. Epub 2022 Jun 29. PubMed PMID: 35767650.
select
2. Smaila BD, Holland SD, Babaeijandaghi F, Henderson HG, Rossi FMV, Ramer MS. Systemic hypoxia mimicry enhances axonal regeneration and functional recovery following peripheral nerve injury. Exp Neurol. 2020 Dec;334:113436. doi: 10.1016/j.expneurol.2020.113436. Epub 2020 Aug 16. PubMed PMID: 32814068.
select
3. Pisconti A, Banks GB, Babaeijandaghi F, Betta ND, Rossi FM, Chamberlain JS, Olwin BB. Loss of niche-satellite cell interactions in syndecan-3 null mice alters muscle progenitor cell homeostasis improving muscle regeneration. Skelet Muscle. 2016;6:34. doi: 10.1186/s13395-016-0104-8. eCollection 2016. PubMed PMID: 27757223; PubMed Central PMCID: PMC5064903.
select
4. Lemos DR, Babaeijandaghi F, Low M, Chang CK, Lee ST, Fiore D, Zhang RH, Natarajan A, Nedospasov SA, Rossi FM. Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors. Nat Med. 2015 Jul;21(7):786-94. doi: 10.1038/nm.3869. Epub 2015 Jun 8. PubMed PMID: 26053624.
select
5. Mortazavi H, Babaeijandaghi F, Akbarzadeh M, Rezaei N, Amirzargar AA, Daneshpazhooh M, Jalali A, Hallaji Z. The influence of systemic therapy on the serum levels of IL-6 and IL-8 in pemphigus vulgaris. J Eur Acad Dermatol Venereol. 2013 Mar;27(3):387-90. doi: 10.1111/j.1468-3083.2011.04319.x. Epub 2011 Nov 2. PubMed PMID: 22044642.
select
6. Ahmadbeigi N, Soleimani M, Babaeijandaghi F, Mortazavi Y, Gheisari Y, Vasei M, Azadmanesh K, Rostami S, Shafiee A, Nardi NB. The aggregate nature of human mesenchymal stromal cells in native bone marrow. Cytotherapy. 2012 Sep;14(8):917-24. doi: 10.3109/14653249.2012.689426. Epub 2012 Jun 11. PubMed PMID: 22687188.
select
7. Shabani I, Haddadi-Asl V, Soleimani M, Seyedjafari E, Babaeijandaghi F, Ahmadbeigi N. Enhanced infiltration and biomineralization of stem cells on collagen-grafted three-dimensional nanofibers. Tissue Eng Part A. 2011 May;17(9-10):1209-18. doi: 10.1089/ten.TEA.2010.0356. Epub 2011 Jan 26. PubMed PMID: 21143044.
select
8. Babaeijandaghi F, Shabani I, Seyedjafari E, Naraghi ZS, Vasei M, Haddadi-Asl V, Hesari KK, Soleimani M. Accelerated epidermal regeneration and improved dermal reconstruction achieved by polyethersulfone nanofibers. Tissue Eng Part A. 2010 Nov;16(11):3527-36. doi: 10.1089/ten.TEA.2009.0829. Epub 2010 Aug 30. PubMed PMID: 20624004.
Contact: [email protected]
