Giulia Cordella
Giulia Cordella
[email protected]
MSc in Molecular Biology
Background
I completed my undergraduate studies at Lewis & Clark College with a double Bachelor with honors in Psychology, Neuroscience and World Languages & Literatures. I then moved to Italy for my Masters at the University of Padua. During my graduate studies I received the Erasmus + Traineeship Award that funded my work in the lab of Prof. De Windt and Calore at the University of Maastricht where I worked on characterizing the phenotype of models for arrhythmogenic right ventricular cardiomyopathy harboring pathogenic mutations in desmosomal genes. I then worked at the University of Geneva through the Swiss European Mobility Grant in collaboration with Prof. Bertrand and Dr. Cacialli investigated zebrafish as a model of Tay-Sachs disease and the role of Hexosaminidase A in brain development. I joined the Rossi Lab at the start of 2023, funded by both the Ulisse and VIRS grants.
Research Projects
I am expanding the research on tissue-resident macrophages in Duchenne Muscular Dystrophy (DMD) using mouse models of DMD, with a focus on understanding molecular mechanisms of CSF1R inhibitors to reprogram macrophages response to chronic inflammation as a treatment strategy. I am also involved with investigating the function of cardiac mural cells in the maintenance of blood vessels following myocardial infarction and evaluating the effectiveness of anti-fibrotic and pro-angiogenic drugs. Finally, I am setting up and optimizing different tissue-clearing protocols for the visualization of complete tissues using light-sheet microscopy.
[email protected]
MSc in Molecular Biology
Background
I completed my undergraduate studies at Lewis & Clark College with a double Bachelor with honors in Psychology, Neuroscience and World Languages & Literatures. I then moved to Italy for my Masters at the University of Padua. During my graduate studies I received the Erasmus + Traineeship Award that funded my work in the lab of Prof. De Windt and Calore at the University of Maastricht where I worked on characterizing the phenotype of models for arrhythmogenic right ventricular cardiomyopathy harboring pathogenic mutations in desmosomal genes. I then worked at the University of Geneva through the Swiss European Mobility Grant in collaboration with Prof. Bertrand and Dr. Cacialli investigated zebrafish as a model of Tay-Sachs disease and the role of Hexosaminidase A in brain development. I joined the Rossi Lab at the start of 2023, funded by both the Ulisse and VIRS grants.
Research Projects
I am expanding the research on tissue-resident macrophages in Duchenne Muscular Dystrophy (DMD) using mouse models of DMD, with a focus on understanding molecular mechanisms of CSF1R inhibitors to reprogram macrophages response to chronic inflammation as a treatment strategy. I am also involved with investigating the function of cardiac mural cells in the maintenance of blood vessels following myocardial infarction and evaluating the effectiveness of anti-fibrotic and pro-angiogenic drugs. Finally, I am setting up and optimizing different tissue-clearing protocols for the visualization of complete tissues using light-sheet microscopy.
